Human IL-13Ra1 Protein (ILR-HM2R1)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 53.1nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Ala27-Thr343

Catalog: ILR-HM2R1

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Product Description Recombinant Human IL-13Ra1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala27-Thr343.

Product Background

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.

Product Category

Recombinant Protein

Target

IL-13Ra1
Synonyms IL-13 R alpha 1; IL13R; IL13RA; CT19; IL13RA1; NR4; CD213A1; AI882074

Gene/Protein ID

P78552

Species

Human

Exact Sequence

Ala27-Thr343
Molecular Weight The protein has a predicted MW of 63.4 kDa. Due to glycosylation, the protein migrates to 78-90 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 53.1nM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human IL-13Ra1, hFc Tag captured on Protein A chip, can bind Human IL-13, His Tag with an affinity constant of 53.1nM as determined in a SPR assay (Biacore T200).
The purity of-Human IL-13Ra1 is greater than 95% as determined by SEC-HPLC.
Human IL-13Ra1 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

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