Name: Human Siglec-4a/MAG Protein (SIG-HM24A)
Brand: KactusBio
SKU: SIG-HM24A-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Siglec-4a, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-4a Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA (QC Test).
Amino Acid Range: Gly20-Pro516

Catalog #SIG-HM24A

Size

100UG

500UG

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Human Siglec-4a/MAG Protein (SIG-HM24A) Summary

Product Description	Recombinant Human Siglec-4a/MAG Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gly20-Pro516.
Product Background	Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human Siglec-4a/MAG Protein (SIG-HM24A) Specifications/Details

Protein	Siglec-4a/MAG
Synonyms	MAG; Siglec4a; Siglec-4a; S-MAG; GMA
Accession	P20916
Species	Human
Biotinylated	no
Amino Acid Range	Gly20-Pro516
Molecular Weight	The protein has a predicted MW of 81.4 kDa. Due to glycosylation, the protein migrates to 100-115 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Siglec-4a, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-4a Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS, 500mM Nacl (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Siglec-4a, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-4a Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA (QC Test).
	Human Siglec-4a on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of-Human Siglec-4a is greater than 95% as determined by SEC-HPLC.