Mouse Activin RIIA/ACVR2A Protein (ARA-MM12A)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human Activin A, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIA, His Tag with the EC50 of 0.13ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Ala20-Pro135

Catalog: ARA-MM12A

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Product Description Recombinant Mouse Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Pro135.

Product Background

Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.

Product Category

Recombinant Protein

Target

Activin RIIA/ACVR2A

Gene/Protein ID

P27038

Species

Mouse

Exact Sequence

Ala20-Pro135
Molecular Weight The protein has a predicted MW of 15.06 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human Activin A, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIA, His Tag with the EC50 of 0.13ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Activin A, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse Activin RIIA, His Tag with the EC50 of 0.13ug/ml determined by ELISA.
The purity of Mouse Activin RIIA is greater than 95% as determined by SEC-HPLC.
Mouse Activin RIIA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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