Mouse B2M/beta 2-Microglobulin Protein (B2M-MM201)
Mouse B2M/beta 2-Microglobulin Protein (B2M-MM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ile21-Met119
Catalog #B2M-MM201
Regular price $231.00
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Mouse B2M/beta 2-Microglobulin Protein (B2M-MM201) Summary

Product Description

Recombinant Mouse B2M/beta 2-Microglobulin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile21-Met119.

Product Background

The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse B2M/beta 2-Microglobulin Protein (B2M-MM201) Specifications/Details

Protein
B2M/beta 2-Microglobulin
Synonyms
Beta-2-microglobulin;B2M;β-2-microglobulin
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ile21-Met119
Molecular Weight
The protein has a predicted MW of 38.4 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse B2M on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse B2M on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse B2M is greater than 95% as determined by SEC-HPLC. The purity of Mouse B2M is greater than 95% as determined by SEC-HPLC.
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