Name: Mouse CD8 alpha&beta Heterodimer Protein (CD8-MM1AB)
Brand: KactusBio
SKU: CD8-MM1AB-100UG
Price: 379.5 USD
Availability: InStock

Mouse CD8 alpha&beta Heterodimer Protein (CD8-MM1AB)

Mouse CD8 alpha&beta Heterodimer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse CD8 alpha&beta Heterodimer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His, C-Flag
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Lys28-Tyr196(CD8 alpha) acidic tail & Leu22-Thr175(CD8 beta) basic tail

Catalog #CD8-MM1AB

Size

100UG

500UG

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Mouse CD8 alpha&beta Heterodimer Protein (CD8-MM1AB) Summary

Product Description	Recombinant Mouse CD8 alpha&beta Heterodimer Protein is expressed from HEK293 with His tag at the C-terminus of CD8 alpha and Flag tag at the C-terminus of CD8 beta.It contains Lys28-Tyr196(CD8 alpha) acidic tail and Leu22-Thr175(CD8 beta) basic tail.
Product Background	CD8 alpha&beta (CD8αβ) is a heterodimeric form of CD8. CD8α is required for surface expression of CD8β. The extracellular IgV-like domain of CD8α interacts with the α3 portion of the class I MHC molecule. CD8αβ is expressed on human peripheral T cells and functions as a coreceptor and can greatly increase the sensitivity and breadth of antigen recognition by CD8+ peripheral T cells bearing TCR.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse CD8 alpha&beta Heterodimer Protein (CD8-MM1AB) Specifications/Details

Protein	CD8 alpha&beta
Synonyms	CD8 alphaβ CD8A&CD8B;
Accession	P01731(CD8 alpha)&P10300(CD8 beta)
Species	Mouse
Biotinylated	no
Amino Acid Range	Lys28-Tyr196(CD8 alpha) acidic tail & Leu22-Thr175(CD8 beta) basic tail
Molecular Weight	The protein has a predicted MW of 24.80 kDa (CD8 alpha) and 23.17 kDa (CD8 beta). Due to glycosylation, the protein migrates to 32-38 kDa and 42-50 kDa based on Bis-Tris PAGE result.
Product Tag	C-His, C-Flag
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Mouse CD8 alpha&beta Heterodimer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse CD8 alpha&beta Heterodimer is greater than 95% as determined by SEC-HPLC.