Mouse IL-11R alpha Protein (ILR-MM111) Summary
Product Description |
Recombinant Mouse IL-11R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Ala372. |
Product Background |
Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse IL-11R alpha Protein (ILR-MM111) Specifications/Details
Protein |
IL-11R alpha |
Synonyms |
IL-11R subunit alpha; IL-11R-alpha; IL-11RA; IL11RA |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ser24-Ala372 |
Molecular Weight |
The protein has a predicted MW of 39.19 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Mouse IL-11R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Mouse IL-11R alpha is greater than 95% as determined by SEC-HPLC. |
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